Published 2023 Jul 29.

Best CBD for Psoriasis 2023: Top 5 Picks

Harry Olson, Edwin Manion and Dale Porter

Dealing with psoriasis can be a challenging and sometimes overwhelming journey. But recent scientific studies point to an exciting new ally in this battle: CBD (Cannabidiol), a compound found in the cannabis plant.

How exactly does CBD help with psoriasis?

Research from various studies like the one conducted in 2019 on the endocannabinoid system in the skin shows that CBD may inhibit keratinocyte proliferation, a key factor in psoriasis.

Studies have also highlighted CBD’s potential anti-inflammatory properties and its ability to aid in skin hydration and elasticity, as found in a study involving 20 patients using CBD-enriched ointment.

These findings offer promising new directions for treating this skin-related condition.

But with so many CBD products on the market, how do you find the right one for your skin?

That’s where we come in! In this article, we’ll guide you through the 5 best CBD products for psoriasis, carefully selected based on scientific research and quality standards.

So, whether you’re new to CBD or looking to refine your current approach, stay tuned as we explore these remarkable options.

Our Process for Selecting the Best CBD for Psoriasis

Choosing the perfect CBD product isn’t easy, given the sheer number of options available today. But don’t fret – we’re here to help. We’ve meticulously examined each product with a stringent set of criteria to ensure quality, safety, and transparency.

Unwavering Quality Standards

Each CBD product that made our list meets these essentials:

  1. It’s made with hemp cultivated right here in the U.S., adhering to high agricultural standards.
  2. It contains no more than 0.3% THC, as verified by its certificate of analysis (COA) – ensuring you don’t get any unwanted psychoactive effects.
  3. It’s cleared tests for pesticides, heavy metals, and molds, in line with the COA, safeguarding you from harmful contaminants.
  4. It’s undergone third-party testing by an ISO 17025-compliant lab, assuring an unbiased quality check.

Delving Deeper into the Details

But we didn’t stop at these basics. We delved further to shortlist products with the following factors in mind:

  1. The potency of each product, because when it comes to CBD, the dosage makes a difference.
  2. The ingredient list: we favored products with ingredients specifically known for stress relief.
  3. The company’s certifications and manufacturing processes to ensure the product comes from trusted, responsible sources.
  4. The reputation of each brand, including customer reviews, giving us a glimpse into real-life user experiences.
  5. A keen eye for red flags, like unsupported health claims about their products or a history of FDA warning letters.

Through this thorough and methodical approach, we’re confident that the products we’ve selected are of the highest quality.

Why Only Five Products in Our Guide?

In the landscape of CBD, options abound. You might stumble upon guides featuring 15, 20, or even more products. But let’s face it, isn’t that a bit excessive?

We understand that the wide array of choices can be overwhelming. And after analyzing dozens of merchants and hundreds of products on the market, we’ve found that high-quality CBD products are, in essence, pretty similar. Their differences often boil down to nuances in taste, nothing more.

So, we took a different approach. We wanted to curate a concise list that won’t drown you in a sea of seemingly endless choices.

So we’ve handpicked only five products. But make no mistake, these are not just any five products. They’re the cream of the crop, the top dogs, the… well, you get the point.

Every product on this list is of the highest quality and offers the best price-per-milligram ratio.

So you can be confident that you’re not just getting the best CBD – you’re also getting the best value for your money. Because we believe that when it comes to your health and wellness journey, less can truly be more.

Best 5 CBD Products Effective for Psoriasis

Multivitamin CBD Gummies For Men

Product URL
Multivitamin CBD Gummies For Men

At a price of $55, the Multivitamin CBD Gummies for Men blend organically-sourced CBD with essential nutrients, such as vitamins A, C, D3, E, B Complex, Pantothenic Acid, Choline, and Zinc. They’re vegan and gluten-free.

The presence of CBD could provide anti-inflammatory effects that help soothe the irritated skin typical of psoriasis. Additionally, the combination of vitamins and minerals supports overall health, possibly enhancing the skin’s appearance and immune function.

Zinc, in particular, is known to promote skin health and may contribute to the healing of psoriasis lesions. These gummies are not only a tasty way to supplement your diet but may also contribute to your wellness routine for better skin health.

CBD Sleep Aid Gummies

Product URL
CBD Sleep Aid Gummies

For $40, the CBD Sleep Aid Gummies combine Superior Broad Spectrum CBD with melatonin and calming herbs, infused with a raspberry flavor. It’s vegan-friendly and gluten-free.

CBD has been researched for its potential to reduce inflammation, which could help alleviate psoriasis symptoms. Plus, the blend of calming herbs may help to ease stress, a known trigger for psoriasis flare-ups.

Proper sleep is vital for skin health, and these gummies might contribute to a restful night. By promoting relaxation and healthy sleep cycles, they could be a natural support for those dealing with psoriasis.

THC Pills Full Spectrum CBD Daily Microdose Blend

Product URL
THC Pills Full Spectrum CBD Daily Microdose Blend

Priced at $70, these capsules contain 25mg full spectrum CBD and 2.5mg of THC per serving. They’re organic and gluten-free.

The combination of THC and CBD may enhance the calming and anti-inflammatory effects that could be beneficial for psoriasis sufferers. This might lead to a decrease in redness and itching associated with the condition.

These capsules aim to provide relaxation and stress relief. As stress is known to exacerbate psoriasis, this blend could be a natural way to manage both mental and skin health.

CBD Gummies with Apple Cider Vinegar

Product URL
CBD Gummies with Apple Cider Vinegar

These $55 CBD Gummies contain 50mg of broad spectrum CBD and 1000mg of apple cider vinegar per serving, along with 80mg of pomegranate and vitamin B12. They’re all-natural, vegan, and gluten-free.

Apple cider vinegar has been used traditionally for various skin conditions, and its acetic acid content may aid in balancing the skin’s pH level. Combined with CBD’s anti-inflammatory properties, this product might support those with psoriasis.

The inclusion of pomegranate, an effective antioxidant, could further boost skin health. These gummies are a novel approach to combine the potential benefits of both CBD and apple cider vinegar for skin care.

CBD Broad Spectrum Gummies – NSF

Product URL
CBD Broad Spectrum Gummies - NSF

Selling at $60, the CBD Broad Spectrum Gummies come with a tasty blend of fruit flavors and are NSF Certified for Sport®, making them suitable for athletes. They’re vegan and made with organic ingredients.

The broad spectrum hemp extract in these gummies may provide relief from inflammation, aiding in the soothing of psoriasis symptoms. CBD’s potential to reduce anxiety and stress could also be beneficial since stress is linked to psoriasis flare-ups.

The NSF Certification assures quality and safety, making these gummies an appealing option for those looking for a reliable and enjoyable way to support skin health.

What the Research Says About CBD and Psoriasis

A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars

https://pubmed.ncbi.nlm.nih.gov/30993303/

The document doesn’t mention the specific year of the study, but it does give a detailed description of what the researchers were doing. They wanted to find out if a special kind of ointment with CBD (a substance found in the cannabis plant) could help with severe skin problems and the scars they leave behind. The researchers focused on two common skin conditions, psoriasis and atopic dermatitis, along with scars resulting from these conditions.

They decided to carry out a study involving 20 patients. Among them, 5 had psoriasis, 5 had atopic dermatitis, and 10 had scars as a result of these skin disorders. The patients were told to put the CBD-enriched ointment on the affected areas of their skin twice a day for three months.

So, what did they find out? The study showed that using the ointment made a big difference! They looked at things like skin hydration, elasticity, and other factors, and even had the patients fill out questionnaires about their symptoms. With the help of photos and the doctors’ assessments, they saw that the ointment significantly improved the skin’s condition and lessened the symptoms of psoriasis and atopic dermatitis. The PASI index score, a way to measure how severe psoriasis is, also got better. Best of all, nobody had allergic or irritant reactions to the ointment during the study.

In conclusion, the researchers found that the CBD ointment (without any THC, another substance found in cannabis) was a safe and effective way to make life better for people with these skin disorders, especially when inflammation was involved. It sounds like the ointment could be a helpful alternative for treating these conditions!

Cannabinoid Signaling in the Skin

https://www.mdpi.com/1420-3049/24/5/918

The study titled “Cannabinoid Signaling in the Skin: Therapeutic Potential of the ‘C(ut)annabinoid’ System” was published on March 6, 2019. It focuses on the endocannabinoid system (ECS), a multifaceted homeostatic regulator that influences various physiological processes throughout the body, including the skin. The researchers explored how the ECS, comprising endocannabinoids (e.g., anandamide), eCB-responsive receptors (e.g., CB1, CB2), and complex enzymes and transporters, is deeply involved in maintaining skin homeostasis, barrier formation, and regeneration.

The study emphasizes that dysregulation of cutaneous cannabinoid signaling can contribute to several prevalent diseases and disorders, such as atopic dermatitis, psoriasis, scleroderma, acne, hair growth and pigmentation disorders, keratin diseases, various tumors, and itch. The ECS is a complex system that includes endogenous ligands, receptors, and a complex enzyme and transporter apparatus. These molecules are involved in the synthesis, cellular uptake, release, inter- and intracellular transport, and degradation of eCBs.

The study also highlights the potential therapeutic applications of cannabinoids, including the Cannabinaceae-derived “classical” (e.g., THC or CBD) and other plant-derived “non-classical” cannabinoids. These cannabinoids can activate, antagonize, or inhibit a wide variety of cellular targets, depending on their concentration, leading to various biological responses.

In the context of skin health, the study suggests that the cutaneous cannabinoid system plays a vital role in the complex protection provided by the skin. It is involved in the communication of several cell types, including immune cells, keratinocytes, fibroblasts, melanocytes, sebocytes, and adipocytes. The study concludes that cutaneous cannabinoid signaling is essential for skin homeostasis and offers promising future research directions for treating skin-related conditions, including psoriasis.

Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/

The document titled “Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders” was published in the journal Clinical, Cosmetic and Investigational Dermatology in the year 2020. It explores the role of the human endocannabinoid system (ECS) in skin biology and the potential therapeutic applications of cannabidiol (CBD), a non-psychoactive compound from the cannabis plant, for various skin and cosmetic disorders.

The study highlights that the ECS plays a critical role in maintaining skin homeostasis and barrier function, and its dysregulation has been implicated in various skin disorders. CBD has gained significant attention for its anecdotal therapeutic potential for skin conditions such as eczema, psoriasis, pruritis, and inflammatory conditions. However, the study emphasizes that confirmed clinical efficacy and the underlying molecular mechanisms have yet to be fully identified.

In terms of detailed results, the document provides insights into the potential of CBD for skin health and specific dermatological conditions. It explains that CBD may have a protective effect against oxidative stress, which can lead to cell damage and chronic inflammation. In vitro studies have shown that CBD can induce the expression of certain genes that play a role in antioxidant defense, such as Hemeoxygenase1 (HMOX1). Topical application of CBD has also been observed to increase levels of specific proteins related to wound repair in mice. Additionally, CBD has demonstrated a protective effect against the reduction of polyunsaturated fatty acids in cell membranes, helping to maintain membrane integrity.

The study also discusses the challenges of transdermal delivery of CBD due to its high lipid/water partitioning but suggests that appropriate carrier systems may overcome this challenge. Some preclinical models have reported successful transdermal delivery of CBD, indicating its potential for topical applications.

In conclusion, the document presents a comprehensive overview of the current understanding of CBD’s potential therapeutic applications for skin health and disorders. While there is evidence to suggest that CBD may be beneficial for certain skin conditions, the study emphasizes the need for further research to confirm its clinical efficacy and understand the underlying mechanisms.

Cannabinoids in the Pathophysiology of Skin Inflammation

https://pubmed.ncbi.nlm.nih.gov/32033005/

The document titled “Cannabinoids in the Pathophysiology of Skin Inflammation” was published on February 4, 2020. It focuses on the complex workings of cannabinoids in the molecular setting of the main dermatological inflammatory diseases, including their interactions with other substances with emerging applications in these conditions. The study also explores the potential role of cannabinoids as antitumor drugs, particularly in relation to the inflammatory component of skin cancer.

The paper details the use of cannabinoids, which are substances that have been used in the treatment of chronic pain, neuropsychiatric disorders, and more recently, skin disorders with an inflammatory component. The study considers in vivo and in vitro research that employed phyto-, endo-, or synthetic cannabinoids. The document emphasizes that cannabinoids are regarded with growing interest as eligible drugs in the treatment of skin inflammatory conditions, with potential anticancer effects.

Specifically, the study delves into the effects of cannabinoids on inflammatory skin disorders, which are a diverse group involving various pathogenic pathways. Cannabinoids seem to exert their properties on cutaneous inflammation in a dose-dependent manner through receptor-dependent and independent mechanisms. The normal skin and its appendages are rich in cannabinoid receptors, and the abundance of these receptors hints at the multiple signaling and regulating functions played by cannabinoids. Benign and malignant skin tumors also express functional cannabinoid receptors, leading to the pursuit of anti-tumoral applications.

The paper also discusses the metabolism of cannabinoids, their interaction with receptors, and their effects on skin inflammation. The study highlights that the skin is more than an effector of the endocannabinoid system (ECS), acting as a regulatory center of cannabinoids metabolism. The cutaneous ECS is involved in skin differentiation, proliferation, and survival, modulating multiple functions of the skin and its appendages.

In conclusion, the study underscores the promising early results of cannabinoids in the treatment of skin inflammatory conditions, including potential anticancer effects. However, it also emphasizes that further controlled human studies are required to establish the definitive role of these products in the pathophysiology of skin inflammation and their usefulness in the clinical setting.

The potential role of cannabinoids in dermatology

https://pubmed.ncbi.nlm.nih.gov/31599175/

The study titled “The potential role of cannabinoids in dermatology” was published online on October 10, 2019. It explores the increasing use of cannabis around the world to treat various skin conditions, focusing on the pharmacology and potential utility of cannabinoids for dermatological conditions like acne, atopic dermatitis, psoriasis, skin cancer, pruritus, and pain.

The authors conducted a literature review, analyzing 44 journal articles published within the last 15 years. They examined the chemical and pharmacological basis of cannabinoids, including three main classes: endocannabinoids, phytocannabinoids, and synthetic cannabinoids. The study also delves into the newly discovered endocannabinoid system in the skin, which suggests that the skin has its receptors for cannabinoids, opening up possibilities for treating various skin conditions.

Regarding psoriasis, the study highlights that cannabinoids may help inhibit keratinocyte proliferation in psoriasis. The primary mechanism is through the peroxisome proliferative-activated receptor gamma (PPARc), and a secondary inhibitory mechanism occurs through down-regulation of keratin K6 and K16 expression by CB-1 activation. Cannabinoids may also exert inhibitory effects on antigen processing and prevent the release of inflammatory cytokines involved in psoriasis, such as IL-2, TNF-alpha, and interferon gamma. Human clinical trials were also mentioned, with AXIM Biotechnologies working on a topical ointment containing cannabigerol and other cannabinoids for psoriasis treatment.

In summary, the study presents a comprehensive overview of the potential role of cannabinoids in treating various skin conditions, including psoriasis. It emphasizes the anti-inflammatory, antipruritic, anti-aging, and anti-malignancy properties of cannabinoids, suggesting promising alternatives to traditional treatments. The findings indicate that cannabinoids could be a valuable tool in dermatology, but further research is needed to fully understand their effects and applications.

Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis

https://pubmed.ncbi.nlm.nih.gov/17157480/

The study you asked me to analyze was published in the “Journal of Dermatological Science” in 2007. It was conducted by researchers at Nottingham University and the University of Reading in the UK, and it focused on the effects of cannabinoids on human keratinocyte proliferation, specifically in relation to psoriasis.

The researchers were interested in cannabinoids, which are compounds found in cannabis, because they are known to have anti-inflammatory properties and inhibitory effects on certain cell lines. They wanted to investigate whether these compounds could be used to treat psoriasis, a common inflammatory skin condition characterized by epidermal keratinocyte hyper-proliferation.

The study looked at four specific cannabinoids: D-9 tetrahydrocannabinol (THC), cannabidiol (CBD), cannabinol (CBN), and cannabigerol (CBG). The researchers used a keratinocyte proliferation assay to test the effects of these compounds on a hyper-proliferating human keratinocyte cell line. They also examined whether the effects were mediated through cannabinoid receptors (CB1 and CB2).

The results of the study showed that all four cannabinoids inhibited keratinocyte proliferation in a concentration-dependent manner. The inhibitory effects were not due to simple cytotoxicity, and the researchers found that the CB receptors did not contribute significantly to the process. Interestingly, the study also indicated that the activity of cannabinoids on keratinocyte proliferation could not be explained by the activation of CB1 or CB2 receptors alone, suggesting a non-classical CB receptor pathway.

In conclusion, the study supported the idea that cannabinoids have a potential therapeutic value in the treatment of psoriasis by inhibiting keratinocyte proliferation. However, the exact mechanism of action is not fully understood, and the researchers suggested that further investigation is needed, possibly involving other receptors like G-protein coupled receptor GPR55 or peroxisome proliferator-activated receptor-gamma (PPAR-g). The findings are promising, but more research is required to fully understand how cannabinoids could be used to treat psoriasis and other skin conditions.

How to Shop for CBD for Psoriasis

When it comes to psoriasis, a chronic skin condition that causes itchy and painful patches, finding the right treatment can be a journey. But have you ever considered CBD products? There are various forms, types, and potencies that might just be suitable for you. Let’s dive into some factors to consider when shopping for a CBD product for psoriasis.

Form

Oil:

CBD oil is a liquid solution that you can take by mouth. It’s made of two parts: a CBD-based extract, and a healthy carrier oil. If you’re looking for something that works fast, CBD oil might be your answer. It can start working in just a few minutes and lasts for 2 – 3 hours. It’s also easy to dose, making it perfect for microdosing. This method can subtly improve focus, productivity, or mood. For psoriasis, the quick action of the oil can bring prompt relief to the itching or discomfort you might be feeling.

Gummies:

If taste is essential to you, CBD gummies could be your go-to. These tasty treats release essential plant compounds slowly over 4 – 6 hours, providing longer relief. They’re easy to dose, portable, and come in various dietary-friendly options, like sugar-free, vegan, or gluten-free. Gummies could be a pleasant way to combat the persistent symptoms of psoriasis without the rush of oil.

Capsules:

CBD capsules offer a mess-free and convenient way to consume CBD, working similarly to any regular capsule or pill. They take about 30-60 minutes to kick in, providing a middle ground between oils and gummies. For those who prefer a traditional method without the taste, capsules might be a wise choice for psoriasis treatment.

Types

Isolate:

If you’re budget-conscious and want a product without THC, CBD isolate could be for you. However, it lacks the potential entourage effect found in other types of CBD, which means it might not be the most potent option for psoriasis.

Full-Spectrum:

Full-spectrum CBD oil includes all cannabinoids, terpenes, and fatty acids from the cannabis plant. This type gives you the benefit of the entourage effect, enhancing its healing properties. A study in 2005 concluded that full-plant extract had greater medicinal properties, potentially offering the best relief for psoriasis symptoms.

Broad-Spectrum:

Broad-spectrum CBD is like a mix between isolate and full-spectrum, containing everything except THC. It might be suitable for those wanting some benefits of the entourage effect without the THC. It won’t show up on a drug test, which might be a consideration for some.

Potency

Potency refers to how strong the CBD product is. Here’s how to understand it:

  • Low-potency CBD oil (300 mg): A great start for general wellness and stress reduction. This might be an option if you’re new to CBD or have mild psoriasis symptoms.
  • Mid-potency CBD oil (600 mg): Suitable for moderate stress and discomfort, making it a good step up if you need something stronger for your psoriasis.
  • High-potency CBD oil (1,000 mg): If you’re dealing with sleep issues or deep muscle soreness along with your psoriasis, this high-strength option could be just what you need.

FAQ

How does CBD help skin conditions like psoriasis?

Studies show CBD reduces inflammation and overactive immune responses associated with psoriasis. It may also decrease rapid skin cell growth. CBD binds to receptors that regulate skin cell production and immune function. More human research is still needed.

What’s the best way to use CBD for the skin?

Topical CBD creams, oils and serums applied directly to the skin allow for targeted absorption. However, oral CBD oils and capsules may also benefit the skin from within. Combine topical and oral products for enhanced effects.

What dose of CBD should I use for my skin?

There are no standard dosing guidelines. For severe localized symptoms, go higher with topicals containing at least 200-500mg CBD. For daily skin maintenance, lower oral doses of 15-50mg may suffice. Increase slowly and monitor results. Discuss optimal dosing with a dermatologist.

How fast does CBD work for skin conditions?

Topical CBD effects are usually noticeable within 15-30 minutes. Oral CBD takes 1-2 hours to kick in. However, achieving full therapeutic effects likely takes 2-4 weeks of consistent CBD use. Give it at least a month before deciding if it works for your skin.

Does CBD absorb through skin into the bloodstream?

Yes, CBD is lipophilic so it can penetrate the outer layer of skin and enter the bloodstream when applied topically. However, much of the applied dose does not reach the blood. Oral use leads to higher blood concentration.

Can CBD treat skin cancer?

No clinical evidence exists that CBD cures skin cancer. However, early research indicates CBD may inhibit the spread of certain skin cancer cells. It also may be useful in managing pain and other symptoms. Talk to an oncologist before using CBD for skin cancer.

Is CBD safe to use on skin long-term?

In most cases, CBD is very well tolerated by the skin without risks of irritation, allergic reactions, phototoxicity or long-term safety concerns. However, more research is still warranted on long-term topical CBD use. Monitor for any skin changes.

Does CBD make you fail a drug test?

Topical CBD use will not make you fail a drug test. However, trace THC in some products may build up over months. Those undergoing testing should use THC-free CBD topicals and discuss oral use with their employer.

Can you use CBD skin products while pregnant?

No, it’s best to avoid CBD during pregnancy as data on safety is lacking. Check with your OB-GYN about any topicals or supplements you’re using. Do not start a new CBD skincare routine if pregnant without medical approval.

Are there drug interactions with topical CBD?

Drug interactions are very unlikely with topical CBD since it absorbs minimally into bloodstream. However, discuss any interactions between oral CBD and your medications with your doctor and pharmacist. Monitor side effects closely if combining.